Scientific publications

Off-the-shelf allogeneic CAR T cells: new development and current challenges

S. Depil, P. Duchateau, S. A. Grupp, G. Mufti and L. Poirot
Nature Review Drug Discovery January 3, 2020
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Repurposing Endogenous Immune Pathways to Tailor and Control Chimeric Antigen Receptor T-cell Functionality

Mohit Sachdeva, Brian W. Busser, Sonal Temburni, Billal Jahangiri, Anne-Sophie Gautron, Alan Maréchal, Alexandre Juillerat, Alan Williams, Stéphane Depil, Philippe Duchateau, Laurent Poirot and Julien Valton
Nature Communications November 2019
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Modulation of Chimeric Antigen Receptor surface expression by a small molecule switch

Alexandre Juillerat, Diane Tkach, Brian W. Busser, Sonal Temburni, Julien Valton, Aymeric Duclert, Laurent Poirot, Stéphane Depil and Philippe Duchateau
BMC Biotechnology (2019); Published Online: https://doi.org/10.1186/s12896-019-0537-3
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Granulocyte-macrophage colony-stimulating factor inactivation in CAR T-Cells prevents monocyte-dependent release of key cytokine release syndrome mediators

Mohit Sachdeva, Philippe Duchateau, Stéphane Depil, Laurent Poirot and Julien Valton
Journal of Biological Chemistry; Published Online: doi: 10.1074/jbc.AC119.007558
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Understanding the indirect DNA read-out specificity of I-CreI Meganuclease

Jesús Prieto, Pilar Redondo, Blanca López-Méndez, Marco D’Abramo, Nekane Merino, Francisco J. Blanco, Phillipe Duchateau, Guillermo Montoya & Rafael Molina
Scientific Reportsvolume 8, Article number: 10286 (2018) July 6, 2018
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