Scientific publications

The CliniBook: Clinical Gene Transfer State of the Art - Chapter: Targeted genome engineering approaches based on rare-cutting endonucleases: a tentative summary

Paques F and Smith J.
Publisher: EDK . pp 341-353 - 2012 November
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Transcription activator-like effector nucleases enable efficient plant genome engineering

Zhang Y, Zhang F, Li X, Baller JA, Qi Y, Starker CG, Bogdanove AJ, Voytas DF.
Plant Physiol. 2013 Jan;161(1):20-7. doi: 10.1104/pp.112.205179.
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Overcoming TALE DNA binding domain sensitivity to methylation

Valton J, Dupuy A, Daboussi F, Thomas S, Maréchal A, Melliand K, Juillerat A, Duchateau P.
Journal of Biological Chemistry 2012 September 26; doi: 10.1074/jbc.C112.408864 jbc.C112.408864.
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Coupling endonucleases with DNA end-processing enzymes drives gene disruption

Certo M.T, Gwiazda K.S, Kuhar R, Sather B, Curinga G, Mandt T, Brault M, Lambert A.R, Baxter S.K, Jacoby K, Ryu B.Y, Kiem H-P, Gouble A, Pâques F, Rawling D.J, Scharenberg A.M.
Nature Methods 9, 973–975 (2012) doi:10.1038/nmeth.2177
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Surface-based cryopreservation strategies for human embryonic stem cells: A comparative study

Malpique R, Tostões R, Beier AF, Serra M, Brito C, Schulz JC, Björquist P, Zimmermann H, Alves PM.
Biotechnol Prog. 2012 Jul;28(4):1079-87. doi: 10.1002/btpr.1572.
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Cytosine-phosphoguanine (CpG) methylation impacts the activity of natural and engineered meganucleases

Valton J, Daboussi F, Leduc S, Redondo P, Molina R, Montoya G & Duchateau P.
Journal of Biological Chemistry 2012 June 27 ; doi: 10.1074/jbc.M112.379966 jbc.M112.379966.
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Human Embryonic Stem Cells Handbook - Volume 873 2012 Chapter 4 : Principles for derivation of human embryonic stem cells

Englund MC, Ellerström C, Andersson K, Noaksson K, Hyllner J.
Methods Mol Biol. 2012; 873:53-68
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Non-specific protein–DNA interactions control I-CreI target binding and cleavage

Molina R, Redondo P, Stella S, Marenchino M, D’Abramo M, Gervasio F, Epinat J-C, Valton J, Grizot S, Duchateau P, Prieto J, and Montoya G.
Nucleic Acids Res (2012) 40 (14): 6936-6945. doi:
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Chromosomal context and epigenetic mechanisms control the efficacy of genome editing by rare-cutting designer endonucleases

Daboussi F, Zaslavskiy M, Poirot L, Loperfido M, Gouble A, Guyot V, Leduc S, Galetto R, Grizot S, Oficjalska D, Perez C, Delacôte F, Dupuy A, Chion-Sotinel I, Le Clerre D, Lebuhotel C, Danos O, Lemaire F, Oussedik K, Cédrone F, Epinat JC, Smith J, Dickson G, Popplewell L, Koo T, Vandendriessche T, Chuah MK, Duclert A, Duchateau P, Pâques F.
Nucleic Acids Res (2012) 40 (13): 6367-6379.
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Human liver spheroids in extended perfusion bioreactor culture

Tostoes RM, Brito C, Leite SB, Serra M, Jensen J, Björquist P, Carrondo MJ, Alves PM.
Hepatology 2012 April; 55(4):1227-36. doi: 10.1002/hep.24760.
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