Scientific publications

TALEN-mediated genetic inactivation of the glucocorticoid receptor in cytomegalovirus-specific T cells

Laurie Menger, Agnes Gouble, Maria A.V. Marzolini, Annette Pachnio, Katharina Bergerhoff, Jake Y. Henry, Julianne Smith, Martin Pule, Paul Moss, Stanley R. Riddell, Sergio A. Quezada, and Karl S. Peggs
Blood October 27, 2015; DOI:
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A TALEN-Exon Skipping Design for a Bethlem Myopathy Model in Zebrafish

Zlatko Radev, Jean-Michel Hermel, Yannick Elipot, Sandrine Bretaud, Sylvain Arnould, Philippe Duchateau, Florence Ruggiero, Jean-Stéphane Joly, Frédéric Sohm
Plos One July 29, 2015; doi: 10.1371/journal.pone.0133986
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Multiplex genome edited T-cell manufacturing platform for “off-the-shelf” adoptive T-cell immunotherapies

Laurent Poirot, Brian Philip, Cécile Schiffer Mannioui, Diane Le Clerre, Isabelle Chion-Sotinel, Sophie Derniame, Pierrick Potrel, Cécile Bas, Laetitia Lemaire, Roman Galetto, Céline Lebuhotel, Justin Eyquem, Gordon Weng-Kit Cheung, Aymeric Duclert, Agnès Gouble, Sylvain Arnould, Karl Peggs, Martin Pule, Andrew M. Scharenberg and Julianne Smith
Cancer Research July 16, 2015; doi: 10.1158/0008-5
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A Multidrug Resistant Engineered CAR T Cell for Allogeneic Combination Immunotherapy

Julien Valton, Valérie Guyot, Alan Marechal, Jean Marie Filhol, Alexandre Juillerat, Aymeric Duclert, Philippe Duchateau and Laurent Poirot
Molecular Therapy, Volume 23, Issue 9, September 2015, Pages 1507–1518
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Improving cold storage and processing traits in potato through targeted gene knockout

Benjamin M. Clasen, Thomas J. Stoddard, Song Luo, Zachary L. Demorest, Jin Li, Frederic Cedrone, Redeat Tibebu, Shawn Davison, Erin E. Ray, Aurelie Daulhac, Andrew Coffman, Ann Yabandith, Adam Retterath, William Haun, Nicholas J. Baltes, Luc Mathis, Daniel F. Voytas and Feng Zhang
Plant Biotechnology Journal April 15 DOI: 10.1111/pbi.12370
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Optimized tuning of TALEN specificity using non-conventional RVDs

Alexandre Juillerat, Coline Pessereau, Gwendoline Dubois, Valérie Guyot, Alan Maréchal, Julien Valton, Fayza Daboussi, Laurent Poirot, Aymeric Duclert & Philippe Duchateau
Scientific Reports 5, Article number: 8150 doi:10.1038/srep08150
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A platform for rapid prototyping of synthetic gene networks in mammalian cells

Xavier Duportet, Liliana Wroblewska, Patrick Guye, Yinqing Li, Justin Eyquem, Julianne Rieders, Tharathorn Rimchala, Gregory Batt & Ron Weiss
Nucleic Acids Res. 2014 Dec 1;42(21):13440-51. doi: 10.1093/nar/gku1082
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Efficient Strategies for TALEN-mediated Genome Editing in Mammalian Cell Lines

Julien Valton, Jean Pierre Cabaniols, Roman Galetto, Fabien Delacote, Marianne Duhamel, Sebastien Paris, Dominique Alain Blanchard, Céline Lebuhotel, Severine Thomas, Sandra Moriceau, Raffy Demirdjian, Gil Letort, Adeline Jacquet, Annabelle Gariboldi, Sandra Rolland, Fayza Daboussi, Alexandre Juillerat, Claudia Bertonati, Aymeric Duclert, Philippe Duchateau
Methods Volume 69, Issue 2, September 2014, Pages 151–170 DOI: 10.1016/j.ymeth.2014.06.013
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Exploring the transcription activator-like effectors scaffold versatility to expand the toolbox of designer nucleases

Alexandre Juillerat, Marine Beurdeley, Julien Valton, Séverine Thomas, Gwendoline Dubois, Mikhail Zaslavskiy, Jérome Mikolajczak, Fabian Bietz, George H Silva, Aymeric Duclert, Fayza Daboussi and Philippe Duchateau
BMC Molecular Biology 2014 doi:10.1186/1471-2199-15-13
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BuD, a helix–loop–helix DNA-binding domain for genome modification

Stefano Stella, Rafael Molina, Blanca López-Méndez, Alexandre Juillerat, Claudia Bertonati, Fayza Daboussi, Ramon Campos-Olivas, Phillippe Duchateau and Guillermo Montoyaa
Acta Crystallogr D Biol Crystallogr. 2014 Jul;70(Pt 7):2042-52. doi: 10.1107/S1399004714011183.
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