Scientific publications

Generation of a High Number of Healthy Erythroid Cells from Gene-Edited Pyruvate Kinase Deficiency Patient-Specific Induced Pluripotent Stem Cells

Zita Garate, Oscar Quintana-Bustamante, Ana M. Crane, Emmanuel Olivier, Laurent Poirot, Roman Galetto, Penelope Kosinski, Collin Hill, Charles Kung, Xabi Agirre, Israel Orman, Laura Cerrato, Omaira Alberquilla, Fatima Rodriguez-Fornes, Noemi Fusaki, Felix Garcia-Sanchez, Tabita M. Maia, Maria L. Ribeiro, Julian Sevilla, Felipe Prosper, Shengfang Jin, Joanne Mountford, Guillermo Guenechea, Agnes Gouble, Juan A. Bueren, Brian R. Davis, Jose C. Segovia
Stem Cell Report Nov. 5 doi: 10.1016/j.stemcr.2015.10.002
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TALEN-mediated genetic inactivation of the glucocorticoid receptor in cytomegalovirus-specific T cells

Laurie Menger, Agnes Gouble, Maria A.V. Marzolini, Annette Pachnio, Katharina Bergerhoff, Jake Y. Henry, Julianne Smith, Martin Pule, Paul Moss, Stanley R. Riddell, Sergio A. Quezada, and Karl S. Peggs
Blood October 27, 2015; DOI:
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A TALEN-Exon Skipping Design for a Bethlem Myopathy Model in Zebrafish

Zlatko Radev, Jean-Michel Hermel, Yannick Elipot, Sandrine Bretaud, Sylvain Arnould, Philippe Duchateau, Florence Ruggiero, Jean-Stéphane Joly, Frédéric Sohm
Plos One July 29, 2015; doi: 10.1371/journal.pone.0133986
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Multiplex genome edited T-cell manufacturing platform for “off-the-shelf” adoptive T-cell immunotherapies

Laurent Poirot, Brian Philip, Cécile Schiffer Mannioui, Diane Le Clerre, Isabelle Chion-Sotinel, Sophie Derniame, Pierrick Potrel, Cécile Bas, Laetitia Lemaire, Roman Galetto, Céline Lebuhotel, Justin Eyquem, Gordon Weng-Kit Cheung, Aymeric Duclert, Agnès Gouble, Sylvain Arnould, Karl Peggs, Martin Pule, Andrew M. Scharenberg and Julianne Smith
Cancer Research July 16, 2015; doi: 10.1158/0008-5
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A Multidrug Resistant Engineered CAR T Cell for Allogeneic Combination Immunotherapy

Julien Valton, Valérie Guyot, Alan Marechal, Jean Marie Filhol, Alexandre Juillerat, Aymeric Duclert, Philippe Duchateau and Laurent Poirot
Molecular Therapy, Volume 23, Issue 9, September 2015, Pages 1507–1518
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Improving cold storage and processing traits in potato through targeted gene knockout

Benjamin M. Clasen, Thomas J. Stoddard, Song Luo, Zachary L. Demorest, Jin Li, Frederic Cedrone, Redeat Tibebu, Shawn Davison, Erin E. Ray, Aurelie Daulhac, Andrew Coffman, Ann Yabandith, Adam Retterath, William Haun, Nicholas J. Baltes, Luc Mathis, Daniel F. Voytas and Feng Zhang
Plant Biotechnology Journal April 15 DOI: 10.1111/pbi.12370
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Optimized tuning of TALEN specificity using non-conventional RVDs

Alexandre Juillerat, Coline Pessereau, Gwendoline Dubois, Valérie Guyot, Alan Maréchal, Julien Valton, Fayza Daboussi, Laurent Poirot, Aymeric Duclert & Philippe Duchateau
Scientific Reports 5, Article number: 8150 doi:10.1038/srep08150
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