28 avril 2022
09:01 E.S.T.

Targeting CD123 in blastic plasmacytoid dendritic cell neoplasm using allogeneic anti-CD123 CAR T cells

Roman Galetto, Agnès Gouble
Nature Communications

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28 avril 2022
09:00 E.S.T.

Allogeneic TCRαβ deficient CAR T-cells targeting CD123 in acute myeloid leukemia

Roman Galetto, Agnès Gouble
Nature Communications

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25 juin 2020
17:44 E.S.T.

Straightforward Generation of Ultrapure Off-the-Shelf Allogeneic CAR-T Cells

Alexandre Juillerat, Diane Tkach, Ming Yang, Alex Boyne, Julien Valton, Laurent Poirot and Philippe Duchateau
Frontiers in Bioengineering and Biotechnology June 25, 2020

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15 juin 2020
11:29 E.S.T.

Allogeneic FLT3 CAR T cells with an off-switch exhibit potent activity against acute myeloid leukemia and can be depleted to expedite bone marrow recovery

Cesar Sommer, Hsin-Yuan Cheng, Duy Nguyen, Danielle Dettling, Yik Andy Yeung, Janette Sutton, Moustafa Hamze, Julien Valton, Julianne Smith, Ivana Djuretic, Javier Chaparro-Riggers, Barbra J. Sasu
Molecular Therapy June 15, 2020

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03 janvier 2020
09:42 E.S.T.

Off-the-shelf allogeneic CAR T cells: new development and current challenges

S. Depil, P. Duchateau, S. A. Grupp, G. Mufti and L. Poirot
Nature Review Drug Discovery January 3, 2020

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19 novembre 2019
10:55 E.S.T.

Repurposing Endogenous Immune Pathways to Tailor and Control Chimeric Antigen Receptor T-cell Functionality

Mohit Sachdeva, Brian W. Busser, Sonal Temburni, Billal Jahangiri, Anne-Sophie Gautron, Alan Maréchal, Alexandre Juillerat, Alan Williams, Stéphane Depil, Philippe Duchateau, Laurent Poirot and Julien Valton
Nature Communications November 2019

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08 juillet 2019
11:13 E.S.T.

Modulation of Chimeric Antigen Receptor surface expression by a small molecule switch

Alexandre Juillerat, Diane Tkach, Brian W. Busser, Sonal Temburni, Julien Valton, Aymeric Duclert, Laurent Poirot, Stéphane Depil and Philippe Duchateau
BMC Biotechnology (2019); Published Online: https://doi.org/10.1186/s12896-019-0537-3

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25 février 2019
17:56 E.S.T.

Granulocyte-macrophage colony-stimulating factor inactivation in CAR T-Cells prevents monocyte-dependent release of key cytokine release syndrome mediators

Mohit Sachdeva, Philippe Duchateau, Stéphane Depil, Laurent Poirot and Julien Valton
Journal of Biological Chemistry; Published Online: doi: 10.1074/jbc.AC119.007558

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Publications scientifiques

Targeting CD123 in blastic plasmacytoid dendritic cell neoplasm using allogeneic anti-CD123 CAR T cells

Allogeneic TCRαβ deficient CAR T-cells targeting CD123 in acute myeloid leukemia

Straightforward Generation of Ultrapure Off-the-Shelf Allogeneic CAR-T Cells

Allogeneic FLT3 CAR T cells with an off-switch exhibit potent activity against acute myeloid leukemia and can be depleted to expedite bone marrow recovery

Off-the-shelf allogeneic CAR T cells: new development and current challenges

Repurposing Endogenous Immune Pathways to Tailor and Control Chimeric Antigen Receptor T-cell Functionality

Modulation of Chimeric Antigen Receptor surface expression by a small molecule switch

Granulocyte-macrophage colony-stimulating factor inactivation in CAR T-Cells prevents monocyte-dependent release of key cytokine release syndrome mediators