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Publications

  • Characterisation of three loci for homologous gene targeting and transgene expression

    Eyquem J, Poirot L, Galetto R, Scharenberg A, Smith J.

    Biotechnology and bioengineering
    2013 March 8; doi:10.1002/bit.24892. Epub ahead of print

    3382
  • Compact designer TALENs for efficient genome engineering

    Beurdeley M, Bietz F, Li J, Thomas S, Stoddard T, Juillerat A, Zhang F, Voytas D.F, Duchateau P, Silva G.H.

    Nature communications
    2013 April 23; doi:10.1038/ncomms2782

    3380
  • Overcoming TALE DNA Binding Domain Sensitivity to Cytosine Methylation

    Julien Valton, Aurélie Dupuy, Fayza Daboussi, Séverine Thomas, Alan Maréchal, Rachel Macmaster, Kevin Melliand, Alexandre Juillerat, and Philippe Duchateau

    First Published on September 26, 2012, doi: 10.1074/jbc.C112.408864   jbc.C112.408864.

    3156
  • Coupling endonucleases with DNA end–processing enzymes to drive gene disruption

    Michael T Certo, Kamila S Gwiazda, Ryan Kuhar, Blythe Sather, Gabrielle Curinga, Tyler Mandt, Michelle Brault, Abigail R Lambert, Sarah K Baxter, Kyle Jacoby, Byoung Y Ryu, Hans-Peter Kiem, Agnes Gouble, Frederic Paques, David J Rawlings & Andrew M Scharenberg

    Nature Methods (2012) doi:10.1038/nmeth.2177

    3099
  • CpG Methylation Impacts the Activity of Natural and Engineered Meganucleases

    Julien Valton, Fayza Daboussi, Sophie Leduc, Pilar Redondo, Rafael Molina, Rachel Macmaster, Frederic Paques, Guillermo Montoya and Philippe Duchateau

    First Published on June 27, 2012, doi: 10.1074/jbc.M112.379966 jbc.M112.379966.

    3054
  • Application of human stem cell-derived cardiomyocytes in safety pharmacology requires caution beyond hERG

    Jonsson MK, Vos MA, Mirams GR, Duker G, Sartipy P, de Boer TP, van Veen TA.

    J Mol Cell Cardiol. 2012 May;52(5):998-1008. Epub 2012 Feb 14.

    2912
  • Non-specific protein-DNA interactions control I-CreI target binding and cleavage.

    Molina R, Redondo P, Stella S, Marenchino M, D'Abramo M, Gervasio FL, Charles Epinat J, Valton J, Grizot S, Duchateau P, Prieto J, Montoya G.

    Nucleic Acids Res. 2012 Apr 11. [Epub ahead of print]

    2892
  • Chromosomal context and epigenetic mechanisms control the efficacy of genome editing by rare-cutting designer endonucleases.

    Daboussi F, Zaslavskiy M, Poirot L, Loperfido M, Gouble A, Guyot V, Leduc S, Galetto R, Grizot S, Oficjalska D, Perez C, Delacôte F, Dupuy A, Chion-Sotinel I, Le Clerre D, Lebuhotel C, Danos O, Lemaire F, Oussedik K, Cédrone F, Epinat JC, Smith J, Dickson G, Popplewell L, Koo T, Vandendriessche T, Chuah MK, Duclert A, Duchateau P, Pâques F.

    Nucleic Acids Res. 2012 Mar 29. [Epub ahead of print]

    2890
  • Comparison of the IKr blockers moxifloxacin, dofetilide and E-4031 in five screening models of pro-arrhythmia reveals lack of specificity of isolated cardiomyocytes

    L Nalos, R Varkevisser, MKB Jonsson, MJC Houtman, JD Beekman, R van der Nagel, MB Thomsen, G Duker, P Sartipy, TP de Boer, M Peschar, MB Rook, TAB van Veen, MAG van der Heyden, MA Vos

    Br J Pharmacol. 2012 Jan;165(2):467-78. doi: 10.1111/j.1476-5381.2011.01558.x.

    2867
  • Free-Form-Fabricated Commercially Pure Ti and Ti6Al4V Porous Scaffolds Support the Growth of Human Embryonic Stem Cell-Derived Mesodermal Progenitors

    G. M. de Peppo,  A. Palmquist,  P. Borchardt,  M. Lennerås,  J. Hyllner, A. Snis, J. Lausmaa, P. Thomsen, 2 and C. Karlsson

    Scientific World Journal. 2012;2012:646417. Epub 2012 Jan 4.

    2850
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