Talens

TALEs (Transcription Activator-Like Effectors) are proteins that bind to DNA in a specific way. TALEs can be converted into DNA scissors by binding them to a Protein domain that has the ability to cleave DNA – in other words a nuclease. TALEN is the acronym for Transcrip¬tion Activator-Like Effector Nuclease. TALENs are sequence-specific and can be modified on demand for targeting a given sequence. Their main advantage is to have a target recognition system based on a simple code, that is therefore easy to forecast. They have a high level of specificity, due in part to the length of their recognition site (between 15 and 20 base pairs), and have numerous applications in Genome engineering. TALENs also have the advantage of being quick and inexpensive to produce on demand.

Please visit Cellectis bioresearch for product related information. For technical enquiries, please contact us.