Careers
Application including C.V and references should be send to :
- Chief Operations Officer - High throughput cell-based platform
- Project manager
- Scientist - Human iPS cells - Project Leader
- Structure-prediction software engineer
- Structural biologist
- Research Assistant
Chief Operations Officer – High throughput cell-based platform
Cellectis is seeking a Chief Operations Officer for its subsidiary, Ectycell, specialized in stem cells.
The successful candidate must have industrial experience in structuring and operating cell culture and test high throughput platforms. Experience in screening of pharmacological compounds, as well as operations under good laboratory practices will be appreciated. The successful candidate will manage Ectycell’s operations and contribute to structuring its platforms.
The ability tackle interdisciplinary problems and strong management skills are essential.
Required diploma:
Engineer or Ph.D. (or equivalent), with experience in industry.
Salary:
Based on experience
Contact : Mention ref CLS_ ETC_COO_2010-01
Project manager
Cellectis is recruiting a project manager to coordinate collaborations in the therapeutic field. The successful candidate will have a PhD in Biology, and at least 4 years of postdoctoral experience in at least one of the following fields: gene therapy, cell therapy, immunology, hematology, hepatology or virology. He/she will report directly to the Chief Scientific Officer and be responsible for the initiation and follow-up of collaborative projects. Only applications including publication lists will be considered.
Required Skills :
- General knowledge of the field of gene and/or cell therapy
- General knowledge of vectorization methods
- Practical experience in one of fields mentioned above
- Excellent oral and written communication skills
- Easy networking and interaction with other people and groups (internal and external)
- An understanding of IP (or strong motivation to learn fast about IP)
Responsibilities
- Document topics of potential interest
- Identify and promote potential collaborations
- Participate in strategic alliance decisions
- Follow-up collaborations, including the management of sponsored collaborative programs
- Interact with internal operational groups, including the scientific teams, and the business development and IP departments
- Prepare reports
Salary:
Based on experience
Contact : Mention ref CLS_ DS_PL_2010-01
Scientist - Human iPS cells - Project Leader
In addition to its commercial (Cellectis BioResearch) and therapeutic (Cellectis Genome Surgery) activities, Cellectis has recently created another subsidiary, Ectycell, especially dedicated to the use of meganucleases with human pluripotent induced stem cells (iPS). Due to their high specificity, these homing endonucleases are perfect tools for genome engineering because they are specific enough to bind and cut one site per genome, therefore normally allowing robustness and reproducibility for such dedicated variable processes.
Ectycell uses customized meganucleases to perform robust and reproducible engineering of iPS cells. This internal development program is also engaged in a partnership program involving other laboratories involved in the field of human stem cells.
Ecycell is seeking an energetic and creative Project Leader to join a group focused on meganuclease-driven targeting in adult somatic cells and iPS cells. The successful candidate must have a strong expertise in the field of human stem cells, preferably pluripotent (ES, iPS). Moreover, the candidate should have already worked in a collaborative environment for the conduction of partnership project(s) with respect of milestones and timelines. The position requires necessarily a very large part of activity at the bench and technical skills that will be shared with other collaborators.
Required diploma:
Ph.D. in cell biology, or a related field, as well as a record of significant postdoctoral and independent research accomplishments as evidenced by a strong publication record. A minimum of five years of work (including the PhD) in program(s) involving human stem cells is required.
Salary:
Based on experience
Contact: Mention ref ECT-PRL_2010-10
Mail : ipsjob@cellectis.com
Cellectis (Ectycell), Parc Biocitech, 102 avenue Gaston Roussel, 93230 Romainville
Structure-prediction software engineer
Cellectis is recruiting a software engineer to join its R&D department. The successful candidate should have a strong background in more than one of the following fields: bioinformatics, computational biology, computer science, engineering, mathematics or physics. Practical knowledge of molecular biology, including experience in a wet lab, would be an advantage.
Required Skills
- Experience in the development of computer simulation methods applied to bio-molecular systems
- Experience with molecular mechanics/dynamics programming (e.g. CHARMM, NAMD, GROMACS)
- Working knowledge of protein-structure prediction and modeling software (e.g. Rosetta, FoldX, Discovery Studio, Maestro); experience programming comparable software highly preferred
- Programming abilities (C, C++, Fortran, scripting languages) under Windows or Linux (preferred)
- An ability to quickly and effectively learn new methods and assimilate techniques into working code
- Easy networking and interaction with other people and groups
- Fluent in English
Responsibilities
- Develop and maintain in-house structure-prediction software
- Propose and design custom software solutions
- Participate in the implementation of novel protein design strategies
- Interact with other teams including the bioinformatics department and application groups
Salary:
Based on experience
Contact : Mention ref CLS_ SPSE_2010-01
Structural biologist
Cellectis is recruiting a Structural Biologist to take part in structure-guided design of novel engineered endonucleases and to participate in the development and validation of innovative protein engineering approaches. The successful candidate should have a PhD in Biochemistry, Molecular Biology or Biophysics, with at least two years of postdoctoral experience. Technical and practical knowledge of structure modeling, simulation and visualization software is essential.
Required Skills
- Practical experience with protein structural biology, including relevant software (e.g. CCP4, O, COOT)
- Practical experience with molecular model building, homology modeling and docking software
- Experience in rational protein design and engineering
- Experience with Linux and one or more scripting languages (e.g. Python, Perl)
- Experience with nucleases and/or proteins that act on nucleic acids
- Experience in protein expression, purification and analysis
- Easy networking and interaction with other people and groups
- Fluent in English
Responsibilities
- Propose and conduct protein design projects
- Interact with other teams including the production platform, the bioinformatics department, and application groups
- Participate in the implementation of novel protein design strategies
- Participate in the transfer of new techniques and strategies to the production platform
- Write patents and publications
Salary:
Based on experience
Contact : Mention ref CLS_ SB_2010-01
Research Assistant
Cellectis is recruiting a research assistant to join its R&D department. The successful candidate will possess at least a B.S. or M.S. degree in Molecular Biology, Biochemistry or a related field, with a minimum of 4 years experience; candidates having received a PhD within the last 2 years will also be considered. Technical knowledge and proven hands-on experience with standard protein biochemistry techniques is essential.
Required skills
- Experience in protein expression and purification
- Experience in protein characterization, including chromatography, electrophoresis, and spectrophotometric methods
- Communication, documentation, and presentation skills
- Easy networking and interaction with other people and groups
- Fluent in English
Responsibilities
- Design and conduct experiments
- Express and purify recombinant proteins
- Characterize biochemical activity of endonucleases
- Characterize purified endonucleases at the biophysical level
- Prepare activity reports
Salary:
Based on experience
Contact : Mention ref CLS_ RA_2010-01
